{"result":[{"researchInterest":"Our research focuses on understanding the regulation of genes associated with cardiovascular development and disease, through the use of cultured cells and tissues and genetically modified mouse models.   A variety of different aberrant pathways are being characterized, including those related to signaling through the bone morphogenetic proteins, serotonin and the S100 family of calcium binding proteins, and those defining how a microtubule associated protein regulates mRNA translation.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=3897&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Marlene_Rabinovitch","appointments":[{"appointment":"Professor,Pediatrics - Cardiology"},{"appointment":"Professor (By courtesy),Developmental Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Cardiology (Heart), Pediatric"},{"focus":"Pediatric Cardiology"}],"firstName":"Marlene","primaryAppointment":"Professor,Pediatrics - Cardiology","displayName":"Marlene Rabinovitch","lastName":"Rabinovitch"},{"researchInterest":"Mechanims (molecular and cellular) of pulmonary hypertension, treatment of pulmonary hypertension, treatment of respiratory failure, treatment of septic shock, hemodynamic monitoring","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4680&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Ronald_Pearl","appointments":[{"appointment":"Professor,Anesthesia"}],"clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care Medicine"}],"firstName":"Ronald","primaryAppointment":"Professor,Anesthesia","displayName":"Ronald Pearl","lastName":"Pearl"},{"researchInterest":"Our research focuses on the pathogenesis and treatment of acute and chronic neonatal lung injury and the mechanisms that regulate lung fluid balance and alveolar & pulmonary vascular development after premature birth.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=3896&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Richard_Bland","appointments":[{"appointment":"Professor (Research),Pediatrics - Neonatology"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"}],"firstName":"Richard","primaryAppointment":"Professor (Research),Pediatrics - Neonatology","displayName":"Richard Bland","lastName":"Bland"},{"researchInterest":"1. Mechanical circulatory support in failing Fontan circulation\r\n2. Pathophysiologic response to fetal cardiac surgery.\r\n3. Various clinical projects in pediatric cardiothoracic surgery","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=5896&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Olaf_Reinhartz","appointments":[{"appointment":"Assistant Professor - Med Center Line,Cardiothoracic Surgery - Pediatric Cardiac Surgery"}],"clinicalFocus":[{"focus":"Cardiothoracic Surgery"},{"focus":"Pediatric Cardiothoracic Surgery"},{"focus":"Pediatric Cardiac Transplantation"}],"firstName":"Olaf","primaryAppointment":"Assistant Professor - Med Center Line,Cardiothoracic Surgery - Pediatric Cardiac Surgery","displayName":"Olaf Reinhartz","lastName":"Reinhartz"},{"researchInterest":"Thesis in the Dept. of Cardiol., JLU Giessen (\u0091Effects of \u0091Statins\u0092 on coagulation param. after HTx\u0092) was followed by a study in pediatric HTx patients (\u0091Adhesion molec. levels in rejection and TxCAD\u0092).  During Residency/Fellowship in Pediatr./Neonatol. her research focused on pulmonary failure and infectious complications (Investigator of the Human Genome Network) in preterm infants. In 08/05 she joined Dr. Bland's group to investigate pulmonary changes after mech. ventilation in newborn mice.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=10142&type=small&showNoImage","href":"http://med.stanford.edu/profiles/Anne_Hilgendorff","appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"clinicalFocus":[],"firstName":"Anne","primaryAppointment":"Postdoctoral Research fellow, Pediatrics","displayName":"Anne Hilgendorff","lastName":"Hilgendorff"},{"researchInterest":"","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=8012&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Carlos_Milla","appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Pulmonary Medicine"}],"clinicalFocus":[{"focus":"Pediatric Pulmonary"},{"focus":"Pulmonary Medicine/Cystic Fibrosis, Pediatric"},{"focus":"Pediatric Lung and Heart-Lung Transplantation"}],"firstName":"Carlos","primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Pulmonary Medicine","displayName":"Carlos Milla","lastName":"Milla"},{"researchInterest":"My research interests include persistent pulmonary hypertension of the newborn, hypoxic respiratory failure, inhaled nitric oxide therapy, ECMO, congenital diaphragmatic hernia, neonatal clinical trials, and the use of aEEG and NIRS to detect brain injury.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4088&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Krisa_Van Meurs","appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Neonatology"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"},{"focus":"neonatal respiratory failure"},{"focus":"persistent pulmonary hypertension of the newborn"},{"focus":"congenital diaphragmatic hernia"},{"focus":"respiratory distress syndrome, newborn"},{"focus":"Extracorporeal Membrane Oxygenation"},{"focus":"neonatal clinical trials"}],"firstName":"Krisa","primaryAppointment":"Professor - Med Center Line,Pediatrics - Neonatology","displayName":"Krisa Van Meurs","lastName":"Van Meurs"},{"researchInterest":"Our translational research program involves molecular, cellular, animal and human studies of endothelial biology. We are focused on the role of nitric oxide synthase (NOS) in atherosclerosis and angiogenesis.  A new focus of investigation has resulted from our discovery of a novel angiogenic pathway mediated by endothelial nicotinic cholinergic receptors (nAChR). We use a wide variety of tools and approaches to investigate the role of NOS and nAChR pathways in cardiovascular biology and disease.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4115&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/John_Cooke","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Cardiology (Heart)"},{"focus":"Cardiology (Heart), Preventive"},{"focus":"Cardiovascular Disease"},{"focus":"Vascular Medicine"}],"firstName":"John","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"John Cooke, MD, PhD","lastName":"Cooke"},{"researchInterest":"Clinical: \r\nPulmonary edema, acute respiratory distress syndromes (ARDS), hyaline membrane disease (HMD), bronchopulmonary dysplasia (BPD)\r\n\r\nBasic Science: \r\nLung epithelial sodium transport","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=8414&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Hugh_O'Brodovich","appointments":[{"appointment":"Professor,Pediatrics"}],"clinicalFocus":[{"focus":"Pediatric Pulmonary"},{"focus":"Pulmonary Medicine/Cystic Fibrosis, Pediatric"}],"firstName":"Hugh","primaryAppointment":"Professor,Pediatrics","displayName":"Hugh O'Brodovich","lastName":"O'Brodovich"},{"researchInterest":"","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4070&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Philip_Tsao","appointments":[{"appointment":"Associate Professor (Research),Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Philip","primaryAppointment":"Associate Professor (Research),Medicine - Cardiovascular Medicine","displayName":"Philip S. Tsao, PhD","lastName":"Tsao"},{"researchInterest":"fetal heart surgery, surgery of premature and very low birthweight neonates, cerebral protection during heart surgery","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=3807&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Vadiyala_Reddy","appointments":[{"appointment":"Associate Professor,Cardiothoracic Surgery - Pediatric Cardiac Surgery"},{"appointment":"Associate Professor,Pediatrics"}],"clinicalFocus":[{"focus":"Cardiac Surgery"},{"focus":"Cardiothoracic Surgery"},{"focus":"Cardiothoracic Surgery, Pediatric "}],"firstName":"Vadiyala","primaryAppointment":"Associate Professor,Cardiothoracic Surgery - Pediatric Cardiac Surgery","displayName":"V. Mohan Reddy","lastName":"Reddy"},{"researchInterest":"Critical Care Medicine,\r\nCardiovascular Pharmacology,\r\nAdrenergic Receptors,\r\nCongestive Heart Failure,\r\nVascular Biology,\r\nCardiopulmonary Physiology,\r\nSepsis","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=6059&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Andrew_Patterson","appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Surgery"}],"clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care Medicine"}],"firstName":"Andrew","primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","displayName":"Andrew J. Patterson, M.D., Ph.D.","lastName":"Patterson"},{"researchInterest":"Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders.  We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4040&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Ricardo_Dolmetsch","appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ricardo","primaryAppointment":"Assistant Professor,Neurobiology","displayName":"Ricardo Dolmetsch","lastName":"Dolmetsch"},{"researchInterest":"We study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function.  Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4176&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Richard_Lewis","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Richard","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Richard Lewis","lastName":"Lewis"},{"researchInterest":"1) Early childhood neurodevelopmental outcomes of ELBW, extremely premature, and high-risk infants; predictive clinical factors, evidence-based interventions \r\n2) Epidemiology of mortality and severe morbidity among extremely preterm infants\r\n3) Use of advanced neuroimaging techniques in the premature and term infant; diagnostic findings, and predictors of neurodevelopmental outcomes\r\n4) Advanced therapeutic modalities: HFOV, iNO, ECMO - implementation, indications, outcomes","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4710&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Susan_Hintz","appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Neonatology"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"},{"focus":"Neonatology"}],"firstName":"Susan","primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Neonatology","displayName":"Susan R. Hintz, M.D., M.S. Epi.","lastName":"Hintz"},{"researchInterest":"1)  Collaborative efforts with Dale Umetsu and Dave Lewis in evaluating alveolar macrophage response to antigen.  We try to examine cytokine activation and inhibition.  I perform bronchoalveolar lavage in these patients in order to obtain alveolar macrophages which we culture, stimulate and study.\r\n2)  Evaluate outcomes for patients admitted to the Pediatric Intensive Care Unit from the EMS services for trauma and other life-threatening events.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4328&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Lorry_Frankel","appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Intensive Care"}],"clinicalFocus":[{"focus":"Intensive Care, Pediatric"},{"focus":"Pediatric Critical Care Medicine"}],"firstName":"Lorry","primaryAppointment":"Professor - Med Center Line,Pediatrics - Intensive Care","displayName":"Lorry Frankel","lastName":"Frankel"},{"researchInterest":"","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=8576&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Franklin_Mullins","appointments":[{"appointment":"Instructor,Pathology"}],"clinicalFocus":[{"focus":"Pathology"},{"focus":"Molecular Pathology"}],"firstName":"Franklin","primaryAppointment":"Instructor,Pathology","displayName":"Franklin Mullins","lastName":"Mullins"},{"researchInterest":"Cardiopulmonary and pulmonary transplant medicine; diagnostic surgical pathology","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4091&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Gerald_Berry","appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"firstName":"Gerald","primaryAppointment":"Professor - Med Center Line,Pathology","displayName":"Gerald Berry","lastName":"Berry"},{"researchInterest":"Dr. Hammer's primary research interests are pediatric pharmacology and perioperative care of children undergoing cardiac surgery. He has numerous funded research projects in these areas, including an NIH grant for $4.3 million to study the pharmacology of sodium nitroprusside, a drug commonly used for blood pressure control in the operating room and ICU. Dr. Hammer has several grants and ongoing research projects in the area of perioperative pain management and physiologic monitoring.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4201&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Gregory_Hammer","appointments":[{"appointment":"Professor - Med Center Line,Anesthesia"},{"appointment":"Professor - Med Center Line (By courtesy),Pediatrics"}],"clinicalFocus":[{"focus":"Anesthesia"}],"firstName":"Gregory","primaryAppointment":"Professor - Med Center Line,Anesthesia","displayName":"Gregory Hammer","lastName":"Hammer"},{"researchInterest":"Neonatology, pulmonary hypertension of the newborn, infant ventilation, neonatal clinical protocols/clinical pathways.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4645&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/William_Benitz","appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Neonatology"}],"clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"},{"focus":"Neonatology"}],"firstName":"William","primaryAppointment":"Professor - Med Center Line,Pediatrics - Neonatology","displayName":"William Benitz","lastName":"Benitz"},{"researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Richard_Tsien","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Richard","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Richard Tsien","lastName":"Tsien"},{"researchInterest":"Cardiac action potentials; tissue culture, voltage, clamp technique; role of calcium in ischemia arrhythmias; coronary, artery disease; myocardial infarction.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4502&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/William_Clusin","appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[{"focus":"Cardiology (Heart)"},{"focus":"Cardiovascular Disease"}],"firstName":"William","primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","displayName":"William Clusin, MD","lastName":"Clusin"},{"researchInterest":"Research interests include (1) computer simulation and modeling of cardiovascular physiology with specific attention paid to congenital heart disease and its treatment, (2) development and testing of transcatheter therapies for the treatment of congenital heart disease, and (3) the evaluation and treatment of pulmonary hypertension/pulmonary vascular disease.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4396&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Jeffrey_Feinstein","appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Cardiology"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Bioengineering"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Pediatric Cardiology"},{"focus":"Congenital Heart Defects"},{"focus":"Pulmonary Hypertension"},{"focus":"Pulmonary Vascular Disease"},{"focus":"Pulmonary Vascular Abnormalities"},{"focus":"Cardiac Catheterization"},{"focus":"Biomechanical Engineering / Bioengineering"}],"firstName":"Jeffrey","primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Cardiology","displayName":"Jeffrey A. Feinstein, MD, MPH","lastName":"Feinstein"},{"researchInterest":"We are interested in the role of the sympathetic nervous system and its cellular components (adrenergic receptors, G proteins) in regulating cardiac development and function. We utilize gene knockout models to study the role of crosstalk between adrenergic receptors and other signaling pathways (MAPK,Akt,PKC) and in the regulation of intracellular and intramitochondrial calcium. We also develop tools for examination of cardiovascular physiologic parameters in transgenic and knockout mice.","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4174&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Daniel_Bernstein","appointments":[{"appointment":"Professor,Pediatrics - Cardiology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Pediatric Cardiology"},{"focus":"Pediatric Heart Transplantation"},{"focus":"Pediatric Heart Failure"}],"firstName":"Daniel","primaryAppointment":"Professor,Pediatrics - Cardiology","displayName":"Daniel Bernstein","lastName":"Bernstein"},{"researchInterest":"Management of advanced lung disease\r\nLung and heart-lung transplantation\r\nPulmonary hypertension","imageUrl":"http://breathe.stanford.edu/profiles/viewImage?facultyId=4196&type=small&showNoImage","href":"http://breathe.stanford.edu/profiles/Ramona_Doyle","appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Pulmonary & Critical Care Med"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Pediatrics"}],"clinicalFocus":[{"focus":"Heart and Lung Transplantation"},{"focus":"Pulmonary Disease"}],"firstName":"Ramona","primaryAppointment":"Associate Professor - Med Center Line,Medicine - Pulmonary & Critical Care Med","displayName":"Ramona Doyle","lastName":"Doyle"}]}